KRT6A antibody (AA 212-240)

Catalog No. ABIN5533274

This Rabbit Polyclonal antibody specifically detects KRT6A in WB. It exhibits reactivity toward Mouse.

Quick Overview for KRT6A antibody (AA 212-240) (ABIN5533274)

Target: KRT6A (Keratin 6A (KRT6A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT6A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRT6A Antibody

Binding Specificity: AA 212-240

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.44 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Alternative Name: Krt6a

Background: Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77 % of all forms found in epithelia.

Molecular Weight: 59 kDa

Gene ID: 16687

UniProt: P50446