MED17 antibody (AA 332-361)
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- Target See all MED17 Antibodies
- MED17 (Mediator Complex Subunit 17 (MED17))
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Binding Specificity
- AA 332-361
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MED17 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MED17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the Central region of human MED17.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MED17 Primary Antibody
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- Application Notes
- For WB starting dilution is: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- MED17 (Mediator Complex Subunit 17 (MED17))
- Alternative Name
- MED17 (MED17 Products)
- Synonyms
- crsp6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, TRAP80 antibody, 77kDa antibody, C330002H14Rik antibody, Crsp6 antibody, Trap80 antibody, mediator of RNA polymerase II transcription subunit 17 antibody, mediator complex subunit 17 antibody, mediator complex subunit 17 L homeolog antibody, AOR_1_2446154 antibody, VDBG_01663 antibody, med17 antibody, med17.L antibody, MED17 antibody, Med17 antibody
- Background
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
- Molecular Weight
- 73 kDa
- Gene ID
- 9440
- UniProt
- Q9NVC6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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