PRKG1 antibody (C-Term)

Catalog No. ABIN5533946

Product Details anti-PRKG1 Antibody

Target: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Binding Specificity: AA 629-660, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This cGKI (cGKI beta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-660 amino acids from the C-terminal region of human cGKI beta.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.558 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PRKG1

Target: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Alternative Name: cGKI (PRKG1 Products)

Synonyms: prkg1 antibody, zgc:63955 antibody, Pkgi antibody, cGk1 antibody, 1 antibody, PKG antibody, PRKG1B antibody, PRKGR1B antibody, cGK antibody, cGK 1 antibody, cGK1 antibody, cGKI antibody, cGKI-BETA antibody, cGKI-alpha antibody, CGKI antibody, cGKI-beta antibody, AW125416 antibody, Gm19690 antibody, Prkg1b antibody, Prkgr1b antibody, Prkg1beta antibody, protein kinase, cGMP-dependent, type Ia antibody, protein kinase, cGMP-dependent, type I antibody, protein kinase, cGMP-dependent, type 1 antibody, prkg1a antibody, PRKG1 antibody, prkg1 antibody, Prkg1 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Molecular Weight: 76 kDa

Gene ID: 5592

UniProt: Q13976