GJB4 antibody (N-Term)

Catalog No. ABIN5534073

Product Details anti-GJB4 Antibody

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Binding Specificity: AA 90-120, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Connexin 30.3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human Connexin 30.3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Alternative Name: Connexin 30.3 (GJB4 Products)

Synonyms: GJB4 antibody, Cnx30.3 antibody, Cx30.3 antibody, Gjb-4 antibody, CX30.3 antibody, EKV antibody, gap junction protein beta 4 antibody, gap junction protein, beta 4 antibody, GJB4 antibody, Gjb4 antibody

Background: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

Molecular Weight: 30 kDa

Gene ID: 127534

UniProt: Q9NTQ9