GRK4 antibody (C-Term)

Catalog No. ABIN5534316

Product Details anti-GRK4 Antibody

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Binding Specificity: AA 549-577, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This GRK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-577 amino acids from the C-terminal region of human GRK4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Alternative Name: GRK4 (GRK4 Products)

Synonyms: GPRK2L antibody, GPRK4 antibody, GRK4a antibody, IT11 antibody, A830025H08Rik antibody, GRK antibody, Gprk2l antibody, Gprk4 antibody, AMPK antibody, AMPKalpha antibody, CG3051 antibody, DmAMPK alpha antibody, Dmel\\CG3051 antibody, EG:132E8.2 antibody, FBgn0023169 antibody, Gprk-4 antibody, ampk antibody, ampkalpha antibody, dAMPKa antibody, dAMPKalpha antibody, snf1a antibody, gprk4 antibody, gprk4-a antibody, grk4 antibody, GRK4 antibody, gprk4-b antibody, zgc:153020 antibody, gprk2l antibody, grk4a antibody, it11 antibody, G protein-coupled receptor kinase 4 antibody, AMP-activated protein kinase alpha subunit antibody, G protein-coupled receptor kinase 4 L homeolog antibody, G protein-coupled receptor kinase 4 S homeolog antibody, GRK4 antibody, Grk4 antibody, AMPKalpha antibody, grk4.L antibody, grk4.S antibody, grk4 antibody, LOC100540688 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Molecular Weight: 67 kDa

Gene ID: 2868

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling