KHSRP antibody (N-Term)

Catalog No. ABIN5534442

Product Details anti-KHSRP Antibody

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Binding Specificity: AA 94-122, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHSRP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KHSRP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KHSRP.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KHSRP

Target: KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))

Alternative Name: KHSRP (KHSRP Products)

Synonyms: FBP2 antibody, FUBP2 antibody, KSRP antibody, 6330409F21Rik antibody, Fbp2 antibody, Fubp2 antibody, Ksrp antibody, Marta1 antibody, KHSRP antibody, VgRBP71 antibody, fbp2 antibody, ksrp antibody, fubp2 antibody, fc94c12 antibody, wu:fb25b12 antibody, wu:fc10e10 antibody, wu:fc94c12 antibody, zgc:163038 antibody, khsrp-b antibody, KH-type splicing regulatory protein antibody, KH-type splicing regulatory protein L homeolog antibody, KH-type splicing regulatory protein S homeolog antibody, KHSRP antibody, Khsrp antibody, khsrp.L antibody, khsrp antibody, khsrp.S antibody

Background: KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Molecular Weight: 73 kDa

Gene ID: 8570

UniProt: Q92945