ORC2 antibody (AA 208-237)

Catalog No. ABIN5534578

Product Details anti-ORC2 Antibody

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Binding Specificity: AA 208-237

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ORC2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human ORC2L.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ORC2

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Alternative Name: ORC2L (ORC2 Products)

Synonyms: CG3041 antibody, DmORC 2 antibody, DmORC2 antibody, DmOrc2 antibody, DmOrc2p antibody, Dmel\\CG3041 antibody, ORC antibody, ORC2 antibody, Orc-2 antibody, Orc2p antibody, fs(3)293 antibody, fs(3)293-19 antibody, k43 antibody, l(3)88Ab antibody, l(3)A5 antibody, l(3)K43 antibody, l(3)SG44 antibody, l(3)dsl5 antibody, l(3)k43 antibody, orc2 antibody, rDmORC antibody, ATORC2 antibody, F13M22.6 antibody, F13M22_6 antibody, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2 antibody, origin recognition complex second largest subunit 2 antibody, ORC2L antibody, AU041563 antibody, Orc2l antibody, orc2-a antibody, orc2l antibody, xorc2 antibody, Origin recognition complex subunit 2 antibody, origin recognition complex second largest subunit 2 antibody, origin recognition complex subunit 2 antibody, origin recognition complex, subunit 2 antibody, origin recognition complex subunit 2 S homeolog antibody, Orc2 antibody, ORC2 antibody, orc2.S antibody, orc-2 antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.

Molecular Weight: 66 kDa

Gene ID: 4999

UniProt: Q13416