UBE2B antibody (C-Term)

Catalog No. ABIN5534794

Product Details anti-UBE2B Antibody

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Binding Specificity: AA 117-146, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This UBE2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the C-terminal region of human UBE2B.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UBE2B

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Alternative Name: UBE2B (UBE2B Products)

Synonyms: E2-17kDa antibody, HHR6B antibody, HR6B antibody, RAD6B antibody, UBC2 antibody, e2-17kda antibody, hhr6b antibody, hr6b antibody, rad6b antibody, ubc2 antibody, zgc:100921 antibody, 2610301N02Rik antibody, E2-14k antibody, Rad6b antibody, mHR6B antibody, ubiquitin conjugating enzyme E2 B antibody, ubiquitin-conjugating enzyme E2B antibody, ubiquitin-conjugating enzyme E2B (RAD6 homolog) antibody, ubiquitin conjugating enzyme E2 B S homeolog antibody, UBE2B antibody, Ube2b antibody, ube2b antibody, ube2b.S antibody

Target Type: Viral Protein

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100 % identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Molecular Weight: 17 kDa

Gene ID: 7320

UniProt: P63146