MMP24 antibody (AA 396-425)

Catalog No. ABIN5537134

Product Details anti-MMP24 Antibody

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Binding Specificity: AA 396-425

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP24 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MMP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the Central region of human MMP24.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MMP24

Target: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Alternative Name: MMP24 (MMP24 Products)

Synonyms: MMP-24 antibody, MMP25 antibody, MT-MMP 5 antibody, MT-MMP5 antibody, MT5-MMP antibody, MT5MMP antibody, MTMMP5 antibody, AU040325 antibody, Mt5-mmp antibody, si:ch211-239j9.5 antibody, MMP24 antibody, mt3-mmp antibody, matrix metallopeptidase 24 antibody, matrix metallopeptidase 16 S homeolog antibody, MMP24 antibody, Mmp24 antibody, mmp24 antibody, mmp16.S antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).

Molecular Weight: 73 kDa

Gene ID: 10893

UniProt: Q9Y5R2