SRPK3 antibody (AA 285-315)

Catalog No. ABIN5537567

Product Details anti-SRPK3 Antibody

Target: SRPK3 (serine/arginine-Rich Protein Specific Kinase 3 (SRPK3))

Binding Specificity: AA 285-315

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRPK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This STK23 (MSSK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-315 amino acids from the Central region of human STK23 (MSSK1).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SRPK3

Target: SRPK3 (serine/arginine-Rich Protein Specific Kinase 3 (SRPK3))

Alternative Name: STK23 (SRPK3 Products)

Synonyms: mssk1 antibody, stk23 antibody, srpk2a antibody, Mssk1 antibody, Stk23 antibody, MSSK-1 antibody, MSSK1 antibody, STK23 antibody, SRSF protein kinase 3 S homeolog antibody, serine/arginine-rich protein specific kinase 3 antibody, SRSF protein kinase 3 antibody, srpk3.S antibody, Srpk3 antibody, SRPK3 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Molecular Weight: 62 kDa

Gene ID: 26576

UniProt: Q9UPE1