PTPRN2 antibody (N-Term)

Catalog No. ABIN5537770

Product Details anti-PTPRN2 Antibody

Target: PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))

Binding Specificity: AA 161-189, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTPRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the N-terminal region of human PTPRN2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PTPRN2

Target: PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))

Alternative Name: PTPRN2 (PTPRN2 Products)

Synonyms: IA-2beta antibody, IAR antibody, ICAAR antibody, PTPRP antibody, R-PTP-N2 antibody, 4930425H11Rik antibody, IA2beta antibody, PTP-NP antibody, Phol antibody, mKIAA0387 antibody, phogrin antibody, protein tyrosine phosphatase, receptor type N2 antibody, protein tyrosine phosphatase, receptor type, N polypeptide 2 antibody, PTPRN2 antibody, Ptprn2 antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Molecular Weight: 111 kDa

Gene ID: 5799

UniProt: Q92932