B4GALT6 antibody (C-Term)

Catalog No. ABIN5538479

Product Details anti-B4GALT6 Antibody

Target: B4GALT6 (UDP-Gal:betaGlcNAc beta 1,4-Galactosyltransferase, Polypeptide 6 (B4GALT6))

Binding Specificity: AA 319-346, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALT6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This B4GALT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human B4GALT6.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.41 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for B4GALT6

Target: B4GALT6 (UDP-Gal:betaGlcNAc beta 1,4-Galactosyltransferase, Polypeptide 6 (B4GALT6))

Alternative Name: B4GALT6 (B4GALT6 Products)

Synonyms: B4Gal-T6 antibody, beta4Gal-T6 antibody, AA536803 antibody, AU022389 antibody, beta-1,4-galactosyltransferase 6 antibody, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 antibody, B4GALT6 antibody, B4galt6 antibody

Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.

Molecular Weight: 45 kDa

Gene ID: 9331

UniProt: Q9UBX8

Pathways: Glycosaminoglycan Metabolic Process