FLCN antibody (AA 325-354)

Catalog No. ABIN5539360

Product Details anti-FLCN Antibody

Target: FLCN (Folliculin (FLCN))

Binding Specificity: AA 325-354

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the Central region of human FLCN.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN (FLCN Products)

Synonyms: FLCN antibody, flcn antibody, wu:fe38g11 antibody, zgc:136982 antibody, AU014660 antibody, B430214A04Rik antibody, Bhd antibody, FLCL antibody, BHD antibody, folliculin antibody, folliculin S homeolog antibody, FLCN antibody, flcn antibody, flcn.S antibody, Flcn antibody

Target Type: Amino Acid

Background: FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.

Molecular Weight: 64 kDa

Gene ID: 201163

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization