alpha Adaptin antibody (AA 706-727) (Biotin)

Catalog No. ABIN5539682

This Goat Polyclonal antibody specifically detects alpha Adaptin in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for alpha Adaptin antibody (AA 706-727) (Biotin) (ABIN5539682)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This alpha Adaptin antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-alpha Adaptin Antibody (Biotin)

Binding Specificity: AA 706-727

Purpose: AP2A1 (aa706-727), Biotinlyated

Sequence: CELEPPAPES PMALLADPAP AAD.

Specificity: This antibody is expected to recognize reported isoform 1 (NP_055018.2) only.

Cross-Reactivity: Cow, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 110 kDa band observed in Human Brain (Frontal Cortex) lysates (calculated MW of 108 kDa according to NP_055018.2). The same band is observed in Mouse Brain, but not in Mouse Liver or Mouse Kidney lysates. See non-biotinylated parental

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Alternative Name: AP2A1

Background: AP2A1, adaptor related protein complex 2 alpha 1 subunit, ADTAA, AP2-ALPHA, CLAPA1, 100 kDa coated vesicle protein A, adapter-related protein complex 2 alpha-1 subunit, adapter-related protein complex 2 subunit alpha-1, adaptin, alpha A, adaptor protein c

Gene ID: 160

NCBI Accession: NP_055018

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation