Thrombomodulin antibody
Quick Overview for Thrombomodulin antibody (ABIN5540104)
Target
See all Thrombomodulin (THBD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognises Thrombomodulin (TM), a 105 kDa protein.
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Purification
- Ion Exchange Chromatography
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Immunogen
- Eahy 926 cell lines.
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Isotype
- IgG1
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Application Notes
- ELISA.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.22 μm Sterile-filtered PBS. Carrier and preservative free.
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Preservative
- Azide free
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Storage
- 4 °C
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Storage Comment
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
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Expiry Date
- 12 months
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- Thrombomodulin (THBD)
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Alternative Name
- cd141,thbd
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Background
- CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
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UniProt
- P07204
Target
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