AGPS antibody (AA 158-384)

Catalog No. ABIN5540330

This Mouse Monoclonal antibody specifically detects AGPS in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for AGPS antibody (AA 158-384) (ABIN5540330)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AGPS antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: AGPS-03

Product Details anti-AGPS Antibody

Binding Specificity: AA 158-384

Specificity: This antibody recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis.

Purification: Protein-A affinity chromatography (>95% pure by SDS-PAGE)

Immunogen: Recombinant human AGPS (amino acids 158-384)

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry. Western blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Alternative Name: agps,aag5

Background: AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.

UniProt: O00116

Pathways: SARS-CoV-2 Protein Interactome