MAPT antibody

Catalog No. ABIN5541353

This Chicken Polyclonal antibody specifically detects MAPT in WB, IF, ICC and IHC (fro). It exhibits reactivity toward Human and Rat.

Quick Overview for MAPT antibody (ABIN5541353)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Reactivity: Human, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MAPT Antibody

Specificity: Specific for the ~48, 65 & 75 kDa Tau isoforms.

Purification: Ig Fraction

Immunogen: Recombinant full length Human Tau expressed in and purified from E. coli.

Isotype: Ig Fraction

Application Details

Application Notes: Western blotting: 1/10,000. Immunohistochemistry. Immunofluorescence: 1/1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservatives: 10 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: mapt,tau

Background: Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer's disease (AD), Pick's disease and progressive supranuclear palsy.

UniProt: P10636

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size