KLF7 antibody (AA 1-302)

Catalog No. ABIN5541453

Product Details anti-KLF7 Antibody

Target: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Binding Specificity: AA 1-302

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF7 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human KLF7 (1-302aa) purified from E. coli

Clone: AT3G3

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for KLF7

Target: KLF7 (Kruppel-Like Factor 7 (Ubiquitous) (KLF7))

Alternative Name: klf7 (KLF7 Products)

Synonyms: klf7 antibody, MGC64357 antibody, KLF7 antibody, zgc:112027 antibody, uklf antibody, MGC146361 antibody, UKLF antibody, 9830124P08Rik antibody, Kruppel-like factor 7 (ubiquitous) S homeolog antibody, Kruppel like factor 7 antibody, Kruppel-like factor 7a antibody, Kruppel-like factor 7 (ubiquitous) antibody, klf7.S antibody, KLF7 antibody, klf7a antibody, klf7 antibody, Klf7 antibody

Background: KLK7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation, survival and the development of nervous systems.and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 is binds specifically to an Ikaros core binding element that is crucial for in vivo NTRK1/TrkA enhancer function. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.

UniProt: O75840