KCND2 antibody (AA 27-184)

Catalog No. ABIN5542461

The Mouse Monoclonal anti-KCND2 antibody is suitable to detect KCND2 in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for KCND2 antibody (AA 27-184) (ABIN5542461)

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KCND2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 5B11B9

Product Details anti-KCND2 Antibody

Binding Specificity: AA 27-184

Purpose: KCND2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KCND2 (AA: 27-184) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KCND2

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Alternative Name: KCND2

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.

Molecular Weight: 70.5 kDa

Gene ID: 3751

UniProt: Q9NZV8