KCND2 antibody (N-Term)

Catalog No. ABIN953000

The Rabbit Polyclonal anti-KCND2 antibody is suitable to detect KCND2 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for KCND2 antibody (N-Term) (ABIN953000)

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCND2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-KCND2 Antibody

Binding Specificity: AA 122-151, N-Term

Specificity: This antibody recognizes Human KCND2 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 122-151 amino acids from the N-terminal region of human KCND2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KCND2

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Alternative Name: KCND2

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.Synonyms: KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2

Molecular Weight: 70537 Da

Gene ID: 3751

NCBI Accession: NP_036413