Selenoprotein S antibody (AA 1-187)

Catalog No. ABIN5542695

Product Details anti-Selenoprotein S Antibody

Target: Selenoprotein S (SELS)

Binding Specificity: AA 1-187

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Selenoprotein S antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: VIMP Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human VIMP (AA: 1-187) expressed in E. Coli.

Clone: 5G4A10

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Selenoprotein S

Target: Selenoprotein S (SELS)

Alternative Name: VIMP (SELS Products)

Background: This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 21.2 kDa

Gene ID: 55829

UniProt: Q9BQE4

Pathways: Cellular Response to Molecule of Bacterial Origin, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome