CD48 antibody (Center)

Catalog No. ABIN783454

Product Details anti-CD48 Antibody

Target: CD48

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD48 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects CD48 / SLAMF2 at center. Two isoforms of SLAMF2 are known to exist, this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the center of human CD48 / SLAMF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for CD48

Target: CD48

Alternative Name: CD48 (CD48 Products)

Synonyms: AI449234 antibody, AW610730 antibody, BCM1 antibody, BLAST antibody, BLAST-1 antibody, BLAST1 antibody, Bcm-1 antibody, MEM-102 antibody, SLAMF2 antibody, Sgp-60 antibody, hCD48 antibody, mCD48 antibody, CD48 antigen antibody, Cd48 molecule antibody, CD48 molecule antibody, Cd48 antibody, CD48 antibody

Background: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.Synonyms: B-lymphocyte activation marker BLAST-1, BCM1, BCM1 surface antigen, BLAST1, Leukocyte antigen MEM-102, MEM-102, TCT.1

Gene ID: 962

NCBI Accession: NP_001769

UniProt: P09326