CCDC106 antibody (C-Term)

Catalog No. ABIN783671

Product Details anti-CCDC106 Antibody

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC106 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human CCDC106

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for CCDC106

Target: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Alternative Name: CCDC106 (CCDC106 Products)

Synonyms: im:6909208 antibody, zgc:113396 antibody, HSU79303 antibody, ZNF581 antibody, BC018462 antibody, RGD1566222 antibody, coiled-coil domain containing 106b antibody, coiled-coil domain containing 106 antibody, ccdc106b antibody, CCDC106 antibody, Ccdc106 antibody

Background: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.Synonyms: Coiled-coil domain-containing protein 106

Gene ID: 29903

NCBI Accession: NP_037433

UniProt: Q9BWC9