Recombinant EIF2AK2 antibody (pThr446)

Catalog No. ABIN5557332

This Rabbit Monoclonal antibody specifically detects EIF2AK2 in WB, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Recombinant EIF2AK2 antibody (pThr446) (ABIN5557332)

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EIF2AK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-EIF2AK2 Antibody

Binding Specificity: pThr446

Purpose: Phospho-PKR (Thr446) Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: A synthesized peptide derived from human eIF2A K2 around the phosphorylation site of T446

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Alternative Name: PKR

Background: Synonyms: PKR(T446), PKR(phospho T446), p-PKR(phospho T446), PKR(phospho-Thr446), double-stranded RNA-dependent Protein Kinase, interferon-induced, double-stranded RNA-activated protein kinase isoform a, protein kinase, interferon-inducible double stranded RNA dependent, interferon-inducible elF2alpha kinase, double stranded RNA activated protein kinase, p68 kinase, eIF-2A protein kinase 2, P1/eIF-2A protein kinase, protein kinase RNA-activated, interferon-inducible RNA-dependent protein kinase, EIF2AK2, EIF2AK1, MGC126524, PKR, PRKRv, E2AK2_HUMAN.

Gene ID: 5610

UniProt: P19525

Pathways: DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C