Recombinant Histone H2B antibody

Catalog No. ABIN5557487

The Rabbit Monoclonal anti-Histone H2B antibody (ABIN5557487) specifically detects Histone H2B in WB, IF, ICC, IHC (p), FACS and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Recombinant Histone H2B antibody (ABIN5557487)

Target: Histone H2B

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone H2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Histone H2B Antibody

Purpose: Histone H2B Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant human Histone H2B protein, full length.

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), IHC-P(1 μg/Test), IHC-F(1:200-1000), IF(1:200-1000), Flow-Cyt(1:200-1000), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Histone H2B

Target: Histone H2B

Background:

Synonyms: H2B.1, H2B.1 B, H2B.b, H2B.c, H2B.d, H2B.e, H2B.f, H2B.j, H2B.q, H2BFB, H2BFC, H2BFD, H2BFE, H2BFF, H2BFJ, H2BFO, H2BFQ, H2BFS, HIRIP2, HIST1H2BB, HIST1H2BD, HIST1H2BH, HIST1H2BL, HIST1H2BM, HIST1H2BN, HIST2H2BE, Histone H2B, Histone H2B type 1 B, Histone H2B type 1 D, Histone H2B type 1 H, Histone H2B type 1 L, Histone H2B type 1 M, Histone H2B type 1 N, Histone H2B type 2 E, Histone protein, H2B GL105, H2B histone family member O, H2B histone family member S.

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Gene ID: 3018

UniProt: P33778