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IL1F10 antibody

IL1F10 Reactivity: Human, Mouse ELISA, WB Host: Mouse Monoclonal Nhat-1 unconjugated
Catalog No. ABIN5564279
  • Target See all IL1F10 Antibodies
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    Reactivity
    • 28
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 18
    • 9
    • 1
    Mouse
    Clonality
    • 18
    • 10
    Monoclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This IL1F10 antibody is un-conjugated
    Application
    • 10
    • 9
    • 5
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificity
    Recognizes human and mouse IL-38.
    Cross-Reactivity
    Human, Mouse (Murine)
    Purity
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human IL-38.
    Clone
    Nhat-1
    Isotype
    IgG2b
    Top Product
    Discover our top product IL1F10 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Expiry Date
    12 months
  • Target
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    Alternative Name
    IL-38 (IL1F10 Products)
    Synonyms
    FIL1-theta antibody, IL-1HY2 antibody, IL-38 antibody, IL1-theta antibody, IL1HY2 antibody, interleukin 1 family, member 10 antibody, interleukin 1 family member 10 antibody, Il1f10 antibody, IL1F10 antibody
    Background
    IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
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