Calpain S1 antibody (AA 172-260)

Catalog No. ABIN560162

There are 3+ publications for this product available. The Mouse Monoclonal anti-Calpain S1 antibody is suitable to detect Calpain S1 in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and RNAi.

Quick Overview for Calpain S1 antibody (AA 172-260) (ABIN560162)

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain S1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Clone: 3C4

Product Details anti-Calpain S1 Antibody

Binding Specificity: AA 172-260

Purpose: Mouse monoclonal antibody raised against a partial recombinant CAPNS1.

Sequence: KRWQAIYKQF DTDRSGTICS SELPGAFEAA GFHLNEHLYN MIIRRYSDES GNMDFDNFIS CLVRLDAMFR AFKSLDKDGT GQIQVNIQE

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CAPNS1 (AAH00592, 172 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Calpain S1 antibody (ABIN560162)

Iguchi-Hashimoto, Usui, Yoshifuji, Shimizu, Kobayashi, Ito, Murakami, Shiomi, Yukawa, Kawabata, Nojima, Ohmura, Fujii, Mimori: "Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-?B and increased STAT5 signals." in: PLoS ONE, Vol. 6, Issue 10, pp. e27020, (2011) (PubMed).

Tabata, Tabata, Nakano: "The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice." in: Clinical and experimental immunology, Vol. 162, Issue 3, pp. 560-7, (2010) (PubMed).

Barker, Leonard, Hansen, Trawick, Ingram, Burdett, Lebold, Walker, Traber: "Vitamin E and C supplementation does not ameliorate muscle dysfunction after anterior cruciate ligament surgery." in: Free radical biology & medicine, Vol. 47, Issue 11, pp. 1611-8, (2009) (PubMed).

Target Details for Calpain S1

Target: Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))

Alternative Name: CAPNS1

Background: Full Gene Name: calpain, small subunit 1
Synonyms: 30K,CALPAIN4,CANP,CANPS,CAPN4,CDPS

Gene ID: 826

Pathways: Apoptosis