GADD45A antibody (AA 76-165)

Catalog No. ABIN560584

This Mouse Monoclonal antibody specifically detects GADD45A in WB, ELISA and PLA. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for GADD45A antibody (AA 76-165) (ABIN560584)

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GADD45A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Clone: 3D12

Product Details anti-GADD45A Antibody

Binding Specificity: AA 76-165

Purpose: Mouse monoclonal antibody raised against a partial recombinant GADD45A.

Sequence: TLIQAFCCEN DINILRVSNP GRLAELLLLE TDAGPAASEG AEQPPDLHCV LVTNPHSSQW KDPALSQLIC FCRESRYMDQ WVPVINLPER

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GADD45A (AAH11757, 76 a.a. ~ 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GADD45A antibody (ABIN560584)

Matteucci, Minutolo, Balestrieri, Marino-Merlo, Bramanti, Garaci, Macchi, Mastino: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." in: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).

Al-Romaih, Sadikovic, Yoshimoto, Wang, Zielenska, Squire: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).

Target Details for GADD45A

Target: GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

Alternative Name: GADD45A

Background: Full Gene Name: growth arrest and DNA-damage-inducible, alpha
Synonyms: DDIT1,GADD45

Gene ID: 1647

Pathways: p53 Signaling, Cell Division Cycle