XRCC6 antibody (AA 1-609)

Catalog No. ABIN560973

Cited in 2+ publications. The Mouse Monoclonal anti-XRCC6 antibody (Clone 4C2-1A6) (ABIN560973) specifically detects XRCC6 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for XRCC6 antibody (AA 1-609) (ABIN560973)

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4C2-1A6

Product Details anti-XRCC6 Antibody

Binding Specificity: AA 1-609

Purpose: Mouse monoclonal antibody raised against a full length recombinant XRCC6.

Sequence: MSGWESYYKT EGDEEAEEEQ EENLEASGDY KYSGRDSLIF LVDASKAMFE SQSEDELTPF DMSIQCIQSV YISKIISSDR DLLAVVFYGT EKDKNSVNFK NIYVLQELDN PGAKRILELD QFKGQQGQKR FQDMMGHGSD YSLSEVLWVC ANLFSDVQFK MSHKRIMLFT NEDNPHGNDS AKASRARTKA GDLRDTGIFL DLMHLKKPGG FDISLFYRDI ISIAEDEDLR VHFEESSKLE DLLRKVRAKE TRKRALSRLK LKLNKDIVIS VGIYNLVQKA LKPPPIKLYR ETNEPVKTKT RTFNTSTGGL LLPSDTKRSQ IYGSRQIILE KEETEELKRF DDPGLMLMGF KPLVLLKKHH YLRPSLFVYP EESLVIGSST LFSALLIKCL EKEVAALCRY TPRRNIPPYF VALVPQEEEL DDQKIQVTPP GFQLVFLPFA DDKRKMPFTE KIMATPEQVG KMKAIVEKLR FTYRSDSFEN PVLQQHFRNL EALALDLMEP EQAVDLTLPK VEAMNKRLGS LVDEFKELVY PPDYNPEGKV TKRKHDNEGS GSKRPKVEYS EEELKTHISK GTLGKFTVPM LKEACRAYGL KSGLKKQELL EALTKHFQD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: XRCC6 (AAH08343.1, 1 a.a. ~ 609 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-XRCC6 antibody (ABIN560973)

Bouchaert, Guerif, Debiais, Irani, Fromont: "DNA-PKcs expression predicts response to radiotherapy in prostate cancer." in: International journal of radiation oncology, biology, physics, Vol. 84, Issue 5, pp. 1179-85, (2012) (PubMed).

Nishii, Nakano, Nakamura, Wate, Shinde, Kaneko, Kusaka: "Myonuclear breakdown in sporadic inclusion body myositis is accompanied by DNA double strand breaks." in: Neuromuscular disorders : NMD, Vol. 21, Issue 5, pp. 345-52, (2011) (PubMed).

Target Details for XRCC6

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Alternative Name: XRCC6

Background: Full Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Synonyms: CTC75,CTCBF,G22P1,KU70,ML8,TLAA

Gene ID: 2547

Pathways: DNA Damage Repair