RUNX3 antibody (AA 294-429)

Catalog No. ABIN5611280

This Mouse Monoclonal antibody specifically detects RUNX3 in ELISA, IHC, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for RUNX3 antibody (AA 294-429) (ABIN5611280)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 7E2B8

Product Details anti-RUNX3 Antibody

Binding Specificity: AA 294-429

Purpose: RUNX3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/50 - 1/250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Alternative Name: RUNX3

Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Molecular Weight: 44.4 kDa

Gene ID: 864

UniProt: Q13761