IGF1 antibody (AA 49-138)

Catalog No. ABIN561442

This Mouse Polyclonal antibody specifically detects IGF1 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for IGF1 antibody (AA 49-138) (ABIN561442)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This IGF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGF1 Antibody

Binding Specificity: AA 49-138

Purpose: Mouse polyclonal antibody raised against a partial recombinant IGF1.

Sequence: GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SRDLRRLEMY CAPLKPTKSA RSVRAQRHTD MPKTQKEVHL

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: IGF1 (NP_000609, 49 a.a. ~ 138 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-IGF1 antibody (ABIN561442)

Herrero-Martín, Osuna, Ordóñez, Sevillano, Martins, Mackintosh, Campos, Madoz-Gúrpide, Otero-Motta, Caballero, Amaral, Wai, Braun, Eisenacher, Schaefer, Poremba, de Alava: "Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target." in: British journal of cancer, Vol. 101, Issue 1, pp. 80-90, (2009) (PubMed).

Target Details for IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Alternative Name: IGF1

Background: Full Gene Name: insulin-like growth factor 1 (somatomedin C)
Synonyms: IGFI

Gene ID: 3479

NCBI Accession: NM_000618

Pathways: RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation