PAI1 antibody (AA 86-185)

Catalog No. ABIN562099

This Mouse Monoclonal antibody specifically detects PAI1 in WB, ELISA and IP. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PAI1 antibody (AA 86-185) (ABIN562099)

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Clone: 3F2

Product Details anti-PAI1 Antibody

Binding Specificity: AA 86-185

Purpose: Mouse monoclonal antibody raised against a partial recombinant SERPINE1.

Sequence: GFKIDDKGMA PALRHLYKEL MGPWNKDEIS TTDAIFVQRD LKLVQGFMPH FFRLFRSTVK QVDFSEVERA RFIINDWVKT HTKGMISNLL GKGAVDQLTR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SERPINE1 (NP_000593, 86 a.a. ~ 185 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PAI1 antibody (ABIN562099)

Slany, Haudek-Prinz, Meshcheryakova, Bileck, Lamm, Zielinski, Gerner, Drach: "Extracellular matrix remodeling by bone marrow fibroblast-like cells correlates with disease progression in multiple myeloma." in: Journal of proteome research, Vol. 13, Issue 2, pp. 844-54, (2014) (PubMed).

Target Details for PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Alternative Name: SERPINE1

Background: Full Gene Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms: PAI,PAI-1,PAI1,PLANH1

Gene ID: 5054

NCBI Accession: NM_000602

Pathways: p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration