PDE3B antibody (AA 401-500)

Catalog No. ABIN562146

Cited in 1 publication. The Mouse Polyclonal anti-PDE3B antibody (ABIN562146) specifically detects PDE3B in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PDE3B antibody (AA 401-500) (ABIN562146)

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This PDE3B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE3B Antibody

Binding Specificity: AA 401-500

Purpose: Mouse polyclonal antibody raised against a partial recombinant PDE3B.

Sequence: LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PDE3B (NP_000913, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PDE3B antibody (ABIN562146)

Bazhin, Kahnert, Kimpfler, Schadendorf, Umansky: "Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells." in: Molecular immunology, Vol. 47, Issue 4, pp. 678-84, (2010) (PubMed).

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B

Background: Full Gene Name: phosphodiesterase 3B, cGMP-inhibited
Synonyms: HcGIP1,cGIPDE1

Gene ID: 5140

NCBI Accession: NM_000922

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process