PDE3B antibody (AA 400-660)

Catalog No. ABIN6145348

The Rabbit Polyclonal anti-PDE3B antibody (ABIN6145348) specifically detects PDE3B in WB. The antibody is reactive with Human samples.

Quick Overview for PDE3B antibody (AA 400-660) (ABIN6145348)

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE3B Antibody

Binding Specificity: AA 400-660

Sequence: PLTPFPGFYP CSEIEDPAEK GDRKLNKGLN RNSLPTPQLR RSSGTSGLLP VEQSSRWDRN NGKRPHQEFG ISSQGCYLNG PFNSNLLTIP KQRSSSVSLT HHVGLRRAGV LSSLSPVNSS NHGPVSTGSL TNRSPIEFPD TADFLNKPSV ILQRSLGNAP NTPDFYQQLR NSDSNLCNSC GHQMLKYVST SESDGTDCCS GKSGEEENIF SKESFKLMET QQEEETEKKD SRKLFQEGDK WLTEEAQSEQ QTNIEQEVSL D

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE3B

Target: PDE3B (phosphodiesterase 3B, CGMP-Inhibited (PDE3B))

Alternative Name: PDE3B

Background: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.,PDE3B,HcGIP1,cGIPDE1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,PDE3B

Molecular Weight: 118 kDa/124 kDa

Gene ID: 5140

UniProt: Q13370

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process