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FAK antibody (AA 355-490)
This Mouse Monoclonal antibody specifically detects FAK in WB, ELISA, IP and PLA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Quick Overview for FAK antibody (AA 355-490) (ABIN562519)
Target
See all FAK (PTK2) Antibodies
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Reactivity
All reactivities for FAK antibodies
Human
Host
All hosts for FAK antibodies
Mouse
Clonality
All clonalities for FAK antibodies
Monoclonal
Conjugate
All conjugates for FAK antibodies
This FAK antibody is un-conjugated
Application
All applications for FAK antibodies
Western Blotting (WB), ELISA, Immunoprecipitation (IP), Proximity Ligation Assay (PLA)
Clone
2C3
Product Details anti-FAK Antibody
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Binding Specificity
All epitopes for FAK antibodies
AA 355-490
Purpose
Mouse monoclonal antibody raised against a partial recombinant PTK2.
Sequence
EGFYPSPQHM VQTNHYQVSG YPGSHGITAM AGSIYPGQAS LLDQTDSWNH RPQEIAMWQP NVEDSTVLDL RGIGQVLPTH LMEERLIRQQ QEMEEDQRWL EKEERFLKPD VRLSRGSIDR EDGSLQGPIG NQHIYQ
Cross-Reactivity
Human
Characteristics
Antibody Reactive Against Recombinant Protein.
Immunogen
PTK2 (AAH28733, 355 a.a. ~ 490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype
IgG1
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
In 1x PBS, pH 7.4
Handling Advice
Aliquot to avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
References for anti-FAK antibody (ABIN562519)
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Li, Fu, Chen, Tan : "JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration. " in: The Journal of biological chemistry , Vol. 285 , Issue 8 , pp. 5472-8 , (2010 ) (PubMed ).
Target Details for FAK
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Target
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Alternative Name
PTK2
Background
Full Gene Name: PTK2 protein tyrosine kinase 2 Synonyms: FADK,FAK,FAK1,pp125FAK
Gene ID
5747
Pathways
Response to Growth Hormone Stimulus , CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
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