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FAK antibody (AA 355-490)

This Mouse Monoclonal antibody specifically detects FAK in WB, ELISA, IP and PLA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Catalog No. ABIN562519

Quick Overview for FAK antibody (AA 355-490) (ABIN562519)

Target

See all FAK (PTK2) Antibodies
FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This FAK antibody is un-conjugated

Application

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Proximity Ligation Assay (PLA)

Clone

2C3
  • Binding Specificity

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    AA 355-490

    Purpose

    Mouse monoclonal antibody raised against a partial recombinant PTK2.

    Sequence

    EGFYPSPQHM VQTNHYQVSG YPGSHGITAM AGSIYPGQAS LLDQTDSWNH RPQEIAMWQP NVEDSTVLDL RGIGQVLPTH LMEERLIRQQ QEMEEDQRWL EKEERFLKPD VRLSRGSIDR EDGSLQGPIG NQHIYQ

    Cross-Reactivity

    Human

    Characteristics

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    PTK2 (AAH28733, 355 a.a. ~ 490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Li, Fu, Chen, Tan: "JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5472-8, (2010) (PubMed).

  • Target

    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

    Alternative Name

    PTK2

    Background

    Full Gene Name: PTK2 protein tyrosine kinase 2
    Synonyms: FADK,FAK,FAK1,pp125FAK

    Gene ID

    5747

    Pathways

    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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