TNF alpha antibody (AA 1-233)

Catalog No. ABIN563205

Cited in 1 publication. The Mouse Monoclonal anti-TNF alpha antibody (Clone M1-C4) (ABIN563205) specifically detects TNF alpha in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TNF alpha antibody (AA 1-233) (ABIN563205)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: M1-C4

Product Details anti-TNF alpha Antibody

Binding Specificity: AA 1-233

Purpose: Mouse monoclonal antibody raised against a full length recombinant TNF.

Sequence: MSTESMIRDV ELAEEALPKK TGGPQGSRRC LFLSLFSFLI VAGATTLFCL LHFGVIGPQR EEFPRDLSLI SPLAQAVRSS SRTPSDKPVA HVVANPQAEG QLQWLNRRAN ALLANGVELR DNQLVVPSEG LYLIYSQVLF KGQGCPSTHV LLTHTISRIA VSYQTKVNLL SAIKSPCQRE TPEGAEAKPW YEPIYLGGVF QLEKGDRLSA EINRPDYLDF AESGQVYFGI IAL

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TNF (AAH28148, 1 a.a. ~ 233 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TNF alpha antibody (ABIN563205)

Ku, Lee, Yoo, Han, Bae: "Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 10, pp. 895-902, (2013) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF

Background: Full Gene Name: tumor necrosis factor (TNF superfamily, member 2)
Synonyms: DIF,TNF-alpha,TNFA,TNFSF2

Gene ID: 7124

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome