IKAP/p150 antibody (AA 148-161)

Catalog No. ABIN636209

Product Details anti-IKAP/p150 Antibody

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Binding Specificity: AA 148-161

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKAP/p150 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogen shares 92 % sequence identity with the rat homolog, and 85 % with the Mouse homolog.

Purification: Affinity chromatography purified

Immunogen: IKAP antibody was raised in rabbit using AA 148-161 IHQDDFGESKFITV of human IKAP as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for IKAP/p150

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Alternative Name: IKAP (ELP1 Products)

Synonyms: DYS antibody, ELP1 antibody, FD antibody, IKAP antibody, IKI3 antibody, TOT1 antibody, IKBKAP antibody, DKFZp469N1415 antibody, 3110040G09Rik antibody, 6030413P05 antibody, C78473 antibody, Elp1 antibody, Ikbkap antibody, elongator complex protein 1 antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein antibody, ielongator complex protein 1 S homeolog antibody, inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein antibody, ELP1 antibody, Elp1 antibody, IKBKAP antibody, elp1.S antibody, elp1 antibody, Ikbkap antibody

Background: IKK-alpha and IKK-beta isozymes are found in large complexes These large, interleukin-1-inducible IKK complexes have been found to contain a new protein, termed IKK-complex-associated protein (IKAP), which can bind NIK and IKKs and assemble them into an active kinase complex. IKAP is a scaffold protein and a regulator for three different kinases involved in pro-inflammatory cytokine signaling.