F13A1 antibody (AA 46-181)

Catalog No. ABIN5646873

Product Details anti-F13A1 Antibody

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Binding Specificity: AA 46-181

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: A human partial recombinant protein corresponding to amino acids 46-181 was used as the immunogen for the Factor XIIIa antibody.

Clone: F13A1-1448

Isotype: IgG2b kappa

Application Details

Application Notes: Titering of the Factor XIIIa antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. ELISA: 2-4 μg/mL, order the BSA-free formulation for coating,Immunofluorescence: 1-2 μg/mL,Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Factor XIIIa antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Factor XIIIa / F13A1 (F13A1 Products)

Synonyms: F13a antibody, f13a1 antibody, wu:fo83d04 antibody, zgc:153334 antibody, F13A1 antibody, F13A antibody, 1200014I03Rik antibody, AI462306 antibody, coagulation factor XIII A1 chain antibody, coagulation factor XIII, A1 polypeptide b antibody, coagulation factor XIII A chain antibody, coagulation factor XIII, A1 subunit antibody, F13a1 antibody, f13a1b antibody, F13A1 antibody

Background: Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.