XRN1 antibody (AA 1455-1706)

Catalog No. ABIN5647152

Product Details anti-XRN1 Antibody

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Binding Specificity: AA 1455-1706

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: A human recombinant protein corresponding to amino acids 1455-1706 was used as the immunogen for the XRN1 antibody.

Clone: 1647CT536-85-48

Isotype: IgG1 kappa

Application Details

Application Notes: Western blot: 1:1000-2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the XRN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Alternative Name: XRN1 (XRN1 Products)

Synonyms: wu:fk92c07 antibody, zgc:63635 antibody, SEP1 antibody, Dhm2 antibody, exo antibody, mXrn1 antibody, RGD1309713 antibody, 5'-3' exoribonuclease 1 antibody, xrn1 antibody, XRN1 antibody, Tsp_05930 antibody, Xrn1 antibody

Background: 5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Gene ID: 54464

UniProt: Q8IZH2