ANAPC11 antibody (AA 56-94)

Catalog No. ABIN5647326

Product Details anti-ANAPC11 Antibody

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Binding Specificity: AA 56-94

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC11 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Bovine,Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 56-94 from the human protein was used as the immunogen for the APC11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000-2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the APC11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ANAPC11

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Alternative Name: APC11 / ANAPC11 (ANAPC11 Products)

Synonyms: APC11 antibody, Apc11p antibody, anapc11 antibody, RGD1561880 antibody, F10A16.17 antibody, F10A16_17 antibody, anaphase-promoting complex/cyclosome 11 antibody, DDBDRAFT_0187183 antibody, DDBDRAFT_0231277 antibody, DDB_0187183 antibody, DDB_0231277 antibody, 1110011I19Rik antibody, R75218 antibody, zgc:153671 antibody, si:dkey-237i9.4 antibody, anaphase promoting complex subunit 11 antibody, anaphase promoting complex subunit 11 L homeolog antibody, anaphase-promoting complex/cyclosome 11 antibody, anaphase-promoting complex subunit Apc11 antibody, ubiquitin-protein ligase Anaphase Promoting Complex antibody, hypothetical protein antibody, predicted protein antibody, anaphase-promoting complex subunit 11 antibody, APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody, ANAPC11 antibody, anapc11.L antibody, anapc11 antibody, Anapc11 antibody, APC11 antibody, apc11 antibody, CAALFM_CR10610CA antibody, LOC9320604 antibody, LOC692923 antibody

Background: Anaphase-promoting complex subunit 11, together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Gene ID: 51529

UniProt: Q9NYG5