DNAJC3 antibody (AA 189-223)

Catalog No. ABIN5647770

Product Details anti-DNAJC3 Antibody

Target: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Binding Specificity: AA 189-223

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Human,Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 189-223 from human DNAJC3 was used as the immunogen for the DNAJC3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the DNAJC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DNAJC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for DNAJC3

Target: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Alternative Name: DNAJC3 (DNAJC3 Products)

Synonyms: ERdj6 antibody, HP58 antibody, P58 antibody, P58IPK antibody, PRKRI antibody, zgc:56356 antibody, zgc:77731 antibody, wu:fb64f06 antibody, DNAJC3 antibody, dnajc3 antibody, DDBDRAFT_0186884 antibody, DDBDRAFT_0233602 antibody, DDB_0186884 antibody, DDB_0233602 antibody, cg8286 antibody, AA408985 antibody, AU067833 antibody, Dnajc3a antibody, Dnajc3b antibody, Prkri antibody, mp58 antibody, p58 antibody, p58IPK antibody, fc17a06 antibody, prkri antibody, wu:fc17a06 antibody, DnaJ heat shock protein family (Hsp40) member C3 antibody, DnaJ (Hsp40) homolog, subfamily C, member 3a antibody, DNAJ heat shock N-terminal domain-containing protein antibody, DnaJ heat shock protein family (Hsp40) member C3 L homeolog antibody, DnaJ (Hsp40) homolog, subfamily C, member 3b antibody, DNAJC3 antibody, dnajc3a antibody, dnajc3 antibody, dnajc3.L antibody, Dnajc3 antibody, dnajc3b antibody

Background: DnaJ homolog subfamily C member 3 is involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.

UniProt: Q13217

Pathways: ER-Nucleus Signaling