SGK1 antibody (N-Term)

Catalog No. ABIN5647813

The Rabbit Polyclonal anti-SGK1 antibody is suitable to detect SGK1 in samples from Human. It has been validated for WB.

Quick Overview for SGK1 antibody (N-Term) (ABIN5647813)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGK1 Antibody

Binding Specificity: N-Term

Purpose: SGK1 Antibody (N-Terminal Region)

Predicted Reactivity: Bovine,Chicken,Mouse,Primate,Rabbit,Rat

Purification: Antigen affinity

Immunogen: The amino acids surrounding serine 78 of human Serum/glucocorticoid-regulated kinase 1 were used as the immunogen for the SGK1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SGK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the SGK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Alternative Name: SGK1

Background: Serum/glucocorticoid-regulated kinase 1 is a serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cellular enzymes, transcription factors, neuronal excitability, cell growth, proliferation, survival, migration and apoptosis. Plays an important role in cellular stress response. Contributes to regulation of renal Na(+) retention, renal K(+) elimination, salt appetite, gastric acid secretion, intestinal Na(+)/H(+) exchange and nutrient transport, insulin-dependent salt sensitivity of blood pressure, salt sensitivity of peripheral glucose uptake, cardiac repolarization and memory consolidation.

UniProt: O00141

Pathways: MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway