MEAF6 antibody (AA 120-154)

Catalog No. ABIN5647858

Product Details anti-MEAF6 Antibody

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Binding Specificity: AA 120-154

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEAF6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Mouse,Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 120-154 from the human protein was used as the immunogen for the MEAF6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000-2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MEAF6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for MEAF6

Target: MEAF6 (MYST/Esa1-Associated Factor 6 (MEAF6))

Alternative Name: MEAF6 / MYST/Esa1-associated factor 6 (MEAF6 Products)

Synonyms: fj63g06 antibody, wu:fj63g06 antibody, zgc:100869 antibody, C1orf149 antibody, CENP-28 antibody, EAF6 antibody, NY-SAR-91 antibody, C3H1orf149 antibody, 2310005N01Rik antibody, 2810036M01Rik antibody, RGD1310440 antibody, MYST/Esa1-associated factor 6 antibody, MYST/Esa1 associated factor 6 antibody, MYST/Esa1-associated factor 6 S homeolog antibody, meaf6 antibody, MEAF6 antibody, meaf6.S antibody, Meaf6 antibody

Background: MYST/Esa1-associated factor 6 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.

Gene ID: 64769

UniProt: Q9HAF1