HBA1 antibody

Catalog No. ABIN5647973

Product Details anti-HBA1 Antibody

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Amino acids V2-R142 from the human alpha subunit were used as the immunogen for the Hemoglobin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Hemoglobin antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Hemoglobin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Alternative Name: Hemoglobin (subunit alpha) (HBA1 Products)

Synonyms: HBA1 antibody, HBAM antibody, Hba-a1 antibody, Hba-a2 antibody, cd31 antibody, hba-a antibody, hba2 antibody, HBH antibody, HBA2 antibody, alpha globin antibody, CD31 antibody, Hba antibody, Hba1 antibody, Hbat1 antibody, AA1 antibody, dZ118J2.2 antibody, HBAI antibody, HBAII antibody, hemoglobin, alpha 1 antibody, hemoglobin subunit alpha 1 antibody, hemoglobin subunit alpha 1 S homeolog antibody, hemoglobin subunit alpha 2 antibody, hemoglobin, alpha 2 antibody, hemoglobin subunit alpha-like antibody, hemoglobin alpha, adult chain 1 antibody, alpha-hemoglobin antibody, hemoglobin subunit alpha antibody, hemoglobin, alpha adult 1 antibody, hemoglobin subunit alpha-2-like antibody, HBA antibody, Hba1 antibody, hba1 antibody, hba1.S antibody, HBA1 antibody, HBA2 antibody, LOC100737768 antibody, Hba-a1 antibody, LOC100472013 antibody, LOC100087130 antibody, hbaa1 antibody, LOC102168959 antibody

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some non-deletion alpha thalassemias have also been reported.

UniProt: P69905