ASIC3 antibody (C-Term)

Catalog No. ABIN5672370

The Rabbit Polyclonal anti-ASIC3 antibody (ABIN5672370) specifically detects ASIC3 in WB. The antibody is reactive with Human samples.

Quick Overview for ASIC3 antibody (C-Term) (ABIN5672370)

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASIC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASIC3 Antibody

Binding Specificity: C-Term

Sequence: LCEVFRDKVL GYFWNRQHSQ RHSSTNLLQE GLGSHRTQVP HLSLGPRPPT

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACCN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Alternative Name: ACCN3

Background: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1

Protein Size: 531

Gene ID: 9311

NCBI Accession: NM_004769, NP_004760

UniProt: Q9UHC3