SWAP70 antibody (AA 131-230) (HRP)

Catalog No. ABIN5675638

The Rabbit Polyclonal anti-SWAP70 antibody is suitable to detect SWAP70 in samples from Human. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for SWAP70 antibody (AA 131-230) (HRP) (ABIN5675638)

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SWAP70 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SWAP70 Antibody (HRP)

Binding Specificity: AA 131-230

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SWAP70

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Alternative Name: SWAP70

Background:

Synonyms: Switch-associated protein 70, SWAP70, SWAP70, KIAA0640, HSPC321

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Gene ID: 23075

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response