SWAP70 antibody (AA 316-585)

Catalog No. ABIN7270654

This Rabbit Polyclonal antibody specifically detects SWAP70 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for SWAP70 antibody (AA 316-585) (ABIN7270654)

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SWAP70 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SWAP70 Antibody

Binding Specificity: AA 316-585

Purpose: SWAP70 Rabbit pAb

Sequence: HKEARQRRKE LRKKQLAEQE ELERQMKELQ AANESKQQEL EAVRKKLEEA ASRAAEEEKK RLQTQVELQA RFSTELEREK LIRQQMEEQV AQKSSELEQY LQRVRELEDM YLKLQEALED ERQARQDEET VRKLQARLLE EESSKRAELE KWHLEQQQAI QTTEAEKQEL ENQRVLKEQA LQEAMEQLEQ LELERKQALE QYEEVKKKLE MATNKTKSWK DKVAHHEGLI RLIEPGSKNP HLITNWGPAA FTEAELEERE KNWKEKKTTE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 316-585 of human SWAP70 (NP_055870.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Alternative Name: SWAP70

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4-bisphosphate production and cell protrusion (By similarity.,SWAP70,HSPC321,SWAP-70,Signal Transduction,Immunology & Inflammation,Neuroscience,Calcium Signaling,SWAP70

Molecular Weight: 68kDa

Gene ID: 23075

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response