PTPRU antibody (AA 579-749)

Catalog No. ABIN5684107

Product Details anti-PTPRU Antibody

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Binding Specificity: AA 579-749

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRU antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human PTPRU (AA: extra 579-749) expressed in E. coli.

Clone: 8H8B2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for PTPRU

Target: PTPRU (Protein Tyrosine Phosphatase, Receptor Type, U (PTPRU))

Alternative Name: PTPRU (PTPRU Products)

Synonyms: FMI antibody, PCP-2 antibody, PTP antibody, PTP-J antibody, PTP-PI antibody, PTP-RO antibody, PTPPSI antibody, PTPRO antibody, PTPU2 antibody, R-PTP-PSI antibody, R-PTP-U antibody, hPTP-J antibody, Ftp-1 antibody, PTP-lambda antibody, PTPlambda antibody, Pcp2 antibody, Ptpf antibody, Ptprl antibody, R-PTP-psi antibody, RPTPlambda antibody, RPTP-psi antibody, fj42a04 antibody, fk66g06 antibody, ptpru antibody, wu:fj42a04 antibody, wu:fk66g06 antibody, protein tyrosine phosphatase, receptor type U antibody, protein tyrosine phosphatase, receptor type, U antibody, protein tyrosine phosphatase, receptor type, U, b antibody, PTPRU antibody, Ptpru antibody, ptprub antibody

Background:

Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Aliases: FMI, PTP, PCP-2, PTP-J, PTPRO, PTPU2, PTP-PI, PTP-RO, PTPPSI, hPTP-J, R-PTP-U, R-PTP-PSI

Molecular Weight: 162.4 kDa

Gene ID: 10076

HGNC: 8792