NEFM antibody (C-Term)

Catalog No. ABIN5688746

The Mouse Monoclonal anti-NEFM antibody (Clone 3H11) (ABIN5688746) specifically detects NEFM in WB and IHC. The antibody is reactive with Human, Rat, Mouse and Chicken samples.

Quick Overview for NEFM antibody (C-Term) (ABIN5688746)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human, Rat, Mouse, Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 3H11

Product Details anti-NEFM Antibody

Binding Specificity: C-Term

Specificity: Specific for the ~145k Neurofilament M protein.

Purification: Total IgG fraction

Immunogen: Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Storage Comment: Neurofilament NF-M antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: Neurofilament NF-M

Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.

Molecular Weight: 145 kDa

Gene ID: 24588

UniProt: P12839

Pathways: Brown Fat Cell Differentiation