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IL36A/IL1F6 antibody (C-Term)
IL1F6
Reactivity: Human
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL36A/IL1F6 Antibody
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Target
See all IL36A/IL1F6 (IL1F6) Antibodies
IL36A/IL1F6 (IL1F6)
(Interleukin 1 Family, Member 6 (IL1F6))
Binding Specificity
All epitopes for IL36A/IL1F6 antibodies
C-Term
Reactivity
All reactivities for IL36A/IL1F6 antibodies
Human
Host
All hosts for IL36A/IL1F6 antibodies
Rabbit
Clonality
All clonalities for IL36A/IL1F6 antibodies
Polyclonal
Conjugate
All conjugates for IL36A/IL1F6 antibodies
This IL36A/IL1F6 antibody is un-conjugated
Application
All applications for IL36A/IL1F6 antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
IL-36A antibody is human specific. IL-36A antibody will not cross-react with IL-36B or IL-36G.
Purification
IL-36A antibody is affinity chromatography purified via peptide column.
Immunogen
IL-36A antibody was raised against an 11 amino acid peptide near the carboxy terminus of human IL-36A. The immunogen is located within the last 50 amino acids of IL-36A.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IL-36A antibody can be used for detection of IL-36A by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
IL-36A antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
IL-36A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for IL36A/IL1F6
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Target
IL36A/IL1F6 (IL1F6)
(Interleukin 1 Family, Member 6 (IL1F6))
Alternative Name
IL-36A (IL1F6 Products )
Synonyms
Il1f6 antibody, Fil1 antibody, IL-1H1 antibody, IL1RP2 antibody, Il1f9 antibody, Il36a antibody, FIL1 antibody, FIL1(EPSILON) antibody, FIL1E antibody, IL-1F6 antibody, IL1(EPSILON) antibody, IL1F6 antibody, interleukin 36, alpha antibody, interleukin 1 family, member 6 (epsilon) antibody, interleukin 1 family, member 6 antibody, interleukin 36 alpha antibody, Il36a antibody, IL1F6 antibody, IL36A antibody, Il1f6 antibody
Background
IL-36A is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36A is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36B and IL-36G, IL-36A requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).
Molecular Weight
Predicted: 17 kDa Observed: 16 kDa
Gene ID
27179
NCBI Accession
NP_055255
UniProt
Q9UHA7
Pathways
Cancer Immune Checkpoints
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